Intravenous-to-enteral drug substitution in the ICU: a single-centre analysis of the potential to reduce the environmental footprint of critical care - Takeaways - MDSpire
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Evaluating the Transition from Intravenous to Enteral Medications in the ICU: A Single-Center Study on Reducing the Environmental Impact of Critical Care

  • By

  • Clémence Marois

  • Maxime Gasperment

  • Adam Celier

  • Ambre Preteux

  • Grégoire Gaucher

  • Léontine Scherer

  • Nicolas Weiss

  • Kevin Bihan

  • Marie Lecronier

  • Amélie Liou

  • September 22, 2026

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  • 1

    Intravenous medications in the ICU significantly contribute to greenhouse gas emissions due to the use of single-use devices.

  • 2

    Out of 269 dispensed intravenous medications, 63 had viable enteral alternatives, with 54 classified as ready for substitution.

  • 3

    If 50% of intravenous administrations were replaced with enteral formulations, greenhouse gas emissions could decrease by 12.7 tCO₂e annually.

  • 4

    The proposed classification for IV-to-enteral substitution aims to assist clinical judgment but requires further validation.

  • 5

    Daily medication reviews in the ICU should assess both the indication for treatment and the appropriateness of the administration route.

Original Source(s)

Intravenous-to-enteral drug substitution in the ICU: a single-centre analysis of the potential to reduce the environmental footprint of critical care

  • by Clémence Marois, Maxime Gasperment, Adam Celier, Ambre Preteux, Grégoire Gaucher, Léontine Scherer, Nicolas Weiss, Kevin Bihan, Marie Lecronier, Amélie Liou

  • September 22, 2026

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