Prognostic impact of persistent postoperative neutrophil-to-lymphocyte ratio elevation 1 year after colorectal cancer surgery - Takeaways - MDSpire

Prognostic impact of persistent postoperative neutrophil-to-lymphocyte ratio elevation 1 year after colorectal cancer surgery

  • By

  • David Ortíz-López

  • Joaquín Marchena-Gómez

  • Yurena Sosa-Quesada

  • Manuel Artiles-Armas

  • Beatriz Arencibia-Pérez

  • Julia Gil-García

  • Eva Nogués-Ramía

  • Cristina Roque-Castellano

  • June 25, 2025

  • 0 min

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  • 1

    Colorectal cancer (CRC) is a leading cause of cancer-related mortality, particularly affecting men under 50 years of age.

  • 2

    The Neutrophil-To-Lymphocyte ratio (NLR) is a significant inflammatory marker associated with poor survival outcomes in CRC patients.

  • 3

    This study investigates the prognostic implications of persistent elevated NLR one year post-surgery for CRC.

  • 4

    Patients with elevated NLR after one year may indicate a poor prognosis, highlighting the need for further research on postoperative inflammation.

  • 5

    The study included 935 patients who underwent curative surgery for CRC, focusing on the evolution of inflammatory markers postoperatively.

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