Survival without major morbidity in extremely preterm infants: a prospective multicenter study in Shenzhen, China - Takeaways - MDSpire

Survival without major morbidity in extremely preterm infants: a prospective multicenter study in Shenzhen, China

  • By

  • Yanping Guo

  • Ying Liu

  • Hua Peng

  • Songzhou Xu

  • Xudong Yan

  • Zhangbin Yu

  • Guobing Chen

  • July 8, 2026

  • 0 min

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  • 1

    The study analyzed outcomes of 314 extremely preterm infants (EPIs) with gestational age < 28 weeks in Shenzhen, China, from January 2022 to December 2023.

  • 2

    The overall survival rate for EPIs was 74.52%, with 234 infants surviving, while 24.20% achieved survival without major morbidity.

  • 3

    Major morbidities among surviving infants included bronchopulmonary dysplasia (48.72%), severe retinopathy of prematurity (42.31%), and sepsis (22.65%).

  • 4

    Antenatal corticosteroid use, increasing gestational age, and higher birth weight were identified as independent protective factors for survival without major morbidity.

  • 5

    The study highlights the need for improved management strategies to enhance survival without major morbidity among EPIs in Shenzhen.

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