The role of 18F-FDG PET/CT in identifying risk factors for ground-glass nodules in invasive lung adenocarcinoma - Takeaways - MDSpire

The role of 18F-FDG PET/CT in identifying risk factors for ground-glass nodules in invasive lung adenocarcinoma

  • By

  • Wenjun Bao

  • Chenmin Ding

  • Nan Li

  • Min Huang

  • Zaosheng Huang

  • Hailong Li

  • Jing Fan

  • Tiantian He

  • Xibao Mao

  • July 7, 2026

  • 0 min

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  • 1

    The study developed an 18F-FDG PET/CT-based predictive model to differentiate high-risk and low-risk invasive lung adenocarcinoma subtypes.

  • 2

    A total of 188 patients with ground-glass nodule-type LUAD were analyzed, divided into training and test cohorts for model validation.

  • 3

    Independent predictors identified included SUVmax, nodule diameter, and lesion location, which were significant for risk stratification.

  • 4

    The original model achieved AUCs of 0.921 in training and 0.855 in testing, with an optimized model slightly improving AUCs.

  • 5

    The study supports the use of PET/CT-derived metrics for non-invasive preoperative risk evaluation in patients with LUAD.

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