A gender-based investigation of risk factors for infectious complications after percutaneous nephrolithotomy for kidney stones: insight for personalized management - Takeaways - MDSpire

A gender-based investigation of risk factors for infectious complications after percutaneous nephrolithotomy for kidney stones: insight for personalized management

  • By

  • Federica Passarelli

  • Ludovico Maria Basadonna

  • Fabio Ciamarra

  • Gianpaolo Lucignani

  • Francesco Ripa

  • Stefano Paolo Zanetti

  • Elisa De Lorenzis

  • Giancarlo Albo

  • Emanuele Montanari

  • Luca Boeri

  • February 18, 2026

  • 0 min

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  • 1

    Percutaneous nephrolithotomy (PCNL) is the preferred treatment for large kidney stones, offering high clearance rates and minimal trauma.

  • 2

    Postoperative fever occurs in 21.0% to 39.8% of PCNL cases and is a predictor of severe infectious outcomes like sepsis.

  • 3

    Female patients have a higher risk of stone-related infections and urosepsis compared to males, due to anatomical and hormonal differences.

  • 4

    The study aims to fill the gap in understanding gender-specific risk factors for infectious complications following PCNL.

  • 5

    Data from 492 patients were analyzed to identify predictors of postoperative infections, emphasizing the need for tailored management.

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