Drug-coated balloons vs. drug-eluting stents for coronary artery disease: an updated systematic review and meta-analysis of randomized controlled trials with lesion-specific insights - Takeaways - MDSpire

Drug-coated balloons vs. drug-eluting stents for coronary artery disease: an updated systematic review and meta-analysis of randomized controlled trials with lesion-specific insights

  • By

  • Yuting Wang

  • Yaqi Shi

  • Qiong Wang

  • Shengxiang Yang

  • Xin Chen

  • May 18, 2026

  • 0 min

Share

  • 1

    Drug-coated balloons (DCB) show higher risks of target lesion revascularization and cardiac death compared to drug-eluting stents (DES) in coronary artery disease.

  • 2

    In-stent restenosis (ISR) treatment is more effective with DES, while DCB is a viable option for de novo small vessel disease.

  • 3

    The increased risk of cardiac death with DCB is primarily associated with paclitaxel-coated balloons, necessitating further investigation.

  • 4

    No significant differences were found in major adverse cardiac events or myocardial infarction between DCB and DES.

  • 5

    Clinical presentation type did not significantly affect treatment outcomes, but analyses were limited by sample size.

Original Source(s)

Drug-coated balloons vs. drug-eluting stents for coronary artery disease: an updated systematic review and meta-analysis of randomized controlled trials with lesion-specific insights

  • by Yuting Wang, Yaqi Shi, Qiong Wang, Shengxiang Yang, Xin Chen

  • May 18, 2026

Related Content

Recent advances in percutaneous coronary intervention for modernizing coronary physiology-guided and device-based strategies for coronary revascularization

J-shaped relationship between creatinine levels and the risk of three major adverse events in patients after percutaneous coronary intervention

Side Effects: Variety Is Overrated

The organ you forgot, the cells that age unevenly, the AI that admits ignorance, and the diet advice that sounds wrong but isn't: medicine's next moves are hiding in plain sight.