A Novel and Reproducible Urinary Diagnostic Framework Reduces Health Care and Antibiotic Utilization for Urinary Tract Infections

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An interdisciplinary clinic developed a standardized urinary infection diagnostic framework (UDF) for managing complex urinary tract infections (UTIs).
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The UDF categorized patients based on anatomic and diagnostic criteria, leading to tailored treatment strategies for UTIs.
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Following the UDF implementation, patients experienced significantly reduced hospitalizations, emergency visits, and antibiotic use for UTIs.
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Among patients receiving prevention therapy for recurrent infections, 69% remained UTI-free at a mean follow-up of 4.6 months.
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The clinic's approach effectively identified noninfectious syndromes in 32% of patients referred for UTIs, highlighting the need for accurate diagnosis.

Open Forum Infectious Diseases

by Kendall Kling, Teresa Zembower, W Justin Moore, Janna Williams, Amanda Vo, Stephanie Colbert, Anthony Schaeffer
May 15, 2025

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