A clustered pulmonary Tuberculosis outbreak at a technical school in Shenzhen, China

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A clustered outbreak of pulmonary tuberculosis was identified in a vocational school class in Shenzhen on June 11, 2025.
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Screening revealed a 9.3% IGRA positivity rate in the first round and 5.1% in the second, with a total of 7 active TB cases confirmed.
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The affected class had a significantly higher IGRA positivity rate of 62.2%, indicating concentrated transmission within that group.
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Whole genome sequencing confirmed a single clonal outbreak of TB with minimal genetic variation among isolates.
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Key strategies for preventing future outbreaks include early surveillance, health education, improved hygiene, and timely treatment of latent infections.

Frontiers In Pediatrics

by Jing Tang, Mingbin Xie, Congyang Li, Fan Huang, Liai Peng, Yali Qu, Jinzhou Mei, Zhenyang Liu, Eryong Liu, Yanfang Guo, Yunxia Wang
May 7, 2026

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