Linking Stages of Cardiovascular-Kidney-Metabolic Syndrome to All-Cause Mortality Risk in U.S. Adults: Findings from a NHANES Cross-Sectional Analysis - Takeaways - MDSpire

Linking Stages of Cardiovascular-Kidney-Metabolic Syndrome to All-Cause Mortality Risk in U.S. Adults: Findings from a NHANES Cross-Sectional Analysis

  • By

  • Yuanze Du

  • Wenxue Sun

  • Jiaqi Zhang

  • Jinfeng Wang

  • Kai Deng

  • Xiaowei Qiao

  • Jie Zhang

  • Xiaofang Zhang

  • Yueyuan Li

  • Xinyu Zhang

  • Xin Yang

  • Fangyu Cheng

  • Zongshuai Wang

  • Chunping Wang

  • March 4, 2026

  • 0 min

Share

  • 1

    The American Heart Association defines Cardiovascular-Kidney-Metabolic syndrome as a systemic disorder involving obesity and metabolic risk factors.

  • 2

    CKM syndrome is classified into five stages, reflecting its progressive nature and the multiplicative burden of associated health conditions.

  • 3

    Approximately 90.8% of U.S. adults were affected by CKM between 2011 and 2022, with significant healthcare costs attributed to these conditions.

  • 4

    Higher stages of CKM syndrome are strongly associated with reduced life expectancy and increased all-cause mortality risk.

  • 5

    This study utilizes NHANES data to explore the relationship between CKM syndrome stages and mortality, addressing a critical research gap.

Original Source(s)

Linking Stages of Cardiovascular-Kidney-Metabolic Syndrome to All-Cause Mortality Risk in U.S. Adults: Findings from a NHANES Cross-Sectional Analysis

  • by Yuanze Du, Wenxue Sun, Jiaqi Zhang, Jinfeng Wang, Kai Deng, Xiaowei Qiao, Jie Zhang, Xiaofang Zhang, Yueyuan Li, Xinyu Zhang, Xin Yang, Fangyu Cheng, Zongshuai Wang, Chunping Wang

  • March 4, 2026

Related Content

Visceral fat area and visceral-to-subcutaneous fat ratio are more strongly associated with residual cholesterol than conventional anthropometric indices in adults with type 2 diabetes

Reorienting catch-up growth research toward early-life prevention of metabolic disorders using natural products

Editorial: Cardiovascular Anthropometry For Large Scale Population Studies Volume II