PET/CT false-negative angioimmunoblastic T-cell lymphoma: a case report and literature review - Takeaways - MDSpire

PET/CT false-negative angioimmunoblastic T-cell lymphoma: a case report and literature review

  • By

  • Yiling Bai

  • Yisong Xiong

  • Hengning Lian

  • Guangqing Shi

  • Yue Teng

  • Lijie Ma

  • July 16, 2026

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  • 1

    Angioimmunoblastic T-cell lymphoma (AITL) is a rare peripheral T-cell lymphoma with heterogeneous clinical presentations.

  • 2

    A 65-year-old female exhibited FDG-negative superficial lymph nodes on PET/CT, complicating her diagnosis of AITL.

  • 3

    Initial biopsies of hypermetabolic deep lymph nodes were non-diagnostic, delaying the definitive diagnosis of AITL.

  • 4

    The case highlights the potential for false-negative PET/CT findings in AITL, necessitating a multimodal diagnostic approach.

  • 5

    Integration of clinical, laboratory, and histopathologic data is essential to avoid diagnostic delays in AITL.

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