Visceral fat area and visceral-to-subcutaneous fat ratio are more strongly associated with residual cholesterol than conventional anthropometric indices in adults with type 2 diabetes - Takeaways - MDSpire

Visceral fat area and visceral-to-subcutaneous fat ratio are more strongly associated with residual cholesterol than conventional anthropometric indices in adults with type 2 diabetes

  • By

  • Zichen Rao

  • Liangyan Hua

  • Yiwei Mo

  • Zhenghao Wu

  • Ziru Fang

  • Chunyan Zhu

  • Lifang Cheng

  • Yiming Zhang

  • May 29, 2026

  • 0 min

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  • 1

    Visceral fat area (VFA) and the visceral-to-subcutaneous fat ratio (VFA/SFA) are strongly associated with residual cholesterol (RC) in adults with type 2 diabetes.

  • 2

    In fully adjusted models, only VFA and VFA/SFA remained independently related to RC, unlike traditional measures such as BMI and waist circumference.

  • 3

    The highest VFA quartile was linked to 0.383 mmol/L higher RC, while the highest VFA/SFA quartile showed a 0.562 mmol/L increase compared to the lowest.

  • 4

    A non-linear association was found between VFA/SFA and RC, with a critical threshold around 0.72 indicating strong links to RC elevation.

  • 5

    Detailed assessment of visceral adiposity may enhance risk stratification for residual cholesterol beyond conventional anthropometric measures.

Original Source(s)

Visceral fat area and visceral-to-subcutaneous fat ratio are more strongly associated with residual cholesterol than conventional anthropometric indices in adults with type 2 diabetes

  • by Zichen Rao, Liangyan Hua, Yiwei Mo, Zhenghao Wu, Ziru Fang, Chunyan Zhu, Lifang Cheng, Yiming Zhang

  • May 29, 2026

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