Impact of Gestational Weight Gain on Pregnancy-Related Breast Cancer and Validation of a Nomogram

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Pregnancy-associated breast cancer (PABC) incidence is rising, with 13 cases per 100,000 deliveries reported in Sweden.
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Gestational weight gain (GWG) is categorized into normal, inadequate, and excessive based on pre-pregnancy BMI guidelines.
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PABC patients diagnosed in late pregnancy or early postpartum experience significantly worse outcomes compared to non-PABC cases.
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A nomogram was developed to estimate disease-free survival in PABC patients, validated using clinical data from 69 cases.
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The study highlights the need for identifying risk factors for PABC due to its association with advanced stages and poor prognosis.

Bmc Cancer

by Chenguang Liu, Ruifeng Wang, Shoujun Wang, Shiyang Liu, Xinhong Wu, Weihong Zheng, Shuyu Li, Tianyao Yu, Jie Hao, Lin Zhang
November 29, 2025

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