Epileptogenic LGG surgery with seizure freedom purpose: Supratotal resection (ETT-SpTR) based on Electrocorticography and navigated transcranial magnetic stimulation - Takeaways - MDSpire

Epileptogenic LGG surgery with seizure freedom purpose: Supratotal resection (ETT-SpTR) based on Electrocorticography and navigated transcranial magnetic stimulation

  • By

  • Francesca Battista

  • Giovanni Muscas

  • Andreea Cristina Aldea

  • Eleonora Visocchi

  • Alberto Parenti

  • Camilla Bonaudo

  • Maddalena Spalletti

  • Riccardo Carrai

  • Giulia Masi

  • Antonio Maiorelli

  • Andrea Amadori

  • Davide Gadda

  • Antonello Grippo

  • Alessandro Della Puppa

  • October 8, 2025

  • 0 min

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  • 1

    Epileptic seizures frequently occur in patients with low-grade glioma (LGG) and can persist even after gross total resection (GTR).

  • 2

    SupraTotal Resection (SpTR) may improve seizure freedom in LGG-related epilepsy by including epileptic foci in the surgical resection.

  • 3

    Intraoperative Electrocorticography (iECoG) and navigated transcranial magnetic stimulation (nTMS) are used to identify and localize epileptic foci during surgery.

  • 4

    The study evaluates the efficacy of iECoG and nTMS in improving surgical outcomes and minimizing postoperative neurological deficits.

  • 5

    Patients underwent comprehensive preoperative assessments, including MRI and EEG, to guide the surgical approach and optimize seizure management.

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