Keratoconus in Hormonal Flux - Takeaways - MDSpire

Keratoconus in Hormonal Flux

Is it time to rethink the importance of hormonal changes on keratoconus pathology?

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1

Keratoconus is often progressive and frequently diagnosed late, lacking universally accepted screening strategies for at-risk individuals.
2

A systematic review highlights the significant role of hormonal fluctuations in the onset and progression of keratoconus.
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The review analyzed 26 studies over six decades, linking keratoconus to hormonal changes, particularly during pregnancy.
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Elevated DHEAS levels were consistently reported in keratoconus patients, indicating a systemic component to the disease.
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The findings suggest integrating hormonal history into keratoconus risk assessments and developing targeted screening pathways.