Keratoconus in Hormonal Flux  - Takeaways - MDSpire

Keratoconus in Hormonal Flux 

Is it time to rethink the importance of hormonal changes on keratoconus pathology?

  • February 12, 2026

  • 3 min

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  • 1

    Keratoconus is often progressive and frequently diagnosed late, lacking universally accepted screening strategies for at-risk individuals.

  • 2

    A systematic review highlights the significant role of hormonal fluctuations in the onset and progression of keratoconus.

  • 3

    The review analyzed 26 studies over six decades, linking keratoconus to hormonal changes, particularly during pregnancy.

  • 4

    Elevated DHEAS levels were consistently reported in keratoconus patients, indicating a systemic component to the disease.

  • 5

    The findings suggest integrating hormonal history into keratoconus risk assessments and developing targeted screening pathways.

Original Source(s)

Keratoconus in Hormonal Flux 

  • February 12, 2026

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