A study on the prognostic assessment of triple-negative breast cancer using habitat analysis of preoperative DCE-MRI subtraction maps - Takeaways - MDSpire

A study on the prognostic assessment of triple-negative breast cancer using habitat analysis of preoperative DCE-MRI subtraction maps

  • By

  • Yiming Yao

  • Junfeng Kong

  • Shanshan Jiang

  • Yuan Sun

  • Wanqiu Zhang

  • Jinding Wei

  • Sen Xing

  • Fangsheng Mou

  • Xinghua Liu

  • Wenbing Zeng

  • July 3, 2026

  • 0 min

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  • 1

    The study evaluated disease-free survival in triple-negative breast cancer using habitat analysis of preoperative DCE-MRI subtraction maps.

  • 2

    A total of 145 patients with TNBC were enrolled, with 29 experiencing recurrence during the study period.

  • 3

    Habitat intratumoral heterogeneity was significantly higher in the high-risk recurrence group compared to the low-risk group (0.59 vs. 0.42, P<0.001).

  • 4

    The area under the ROC curve for habitat intratumoral heterogeneity as a predictor of TNBC recurrence was 0.71 (95% CI: 0.616-0.805, P<0.05).

  • 5

    Habitat intratumoral heterogeneity was identified as an independent predictor of poorer disease-free survival in multivariable analysis (HR 1.465, P=0.013).

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