Confocal laser endomicroscopy for upper tract urothelial carcinoma: validation of the proposed criteria and proposal of a scoring system for real-time tumor grading

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Confocal laser endomicroscopy (CLE) is proposed for real-time grading of upper tract urothelial carcinoma (UTUC) during ureteroscopy.
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The study aims to validate CLE criteria for UTUC and develop a scoring system for more quantifiable grading.
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Histopathologic tumor grade is crucial for risk stratification in UTUC, but current biopsy methods show significant discordance.
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The study uses a 2.7 Fr Uroflex-B probe for CLE imaging, which provides a limited field of view and requires careful assessment.
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Diagnostic accuracy of CLE for UTUC grading will be evaluated against histopathologic results to determine its clinical utility.

World Journal Of Urology

by J. E. Freund, E. I. M. L. Liem, C. D. Savci-Heijink, J. Baard, G. M. Kamphuis, J. J. M. C. H. de la Rosette, D. M. de Bruin
January 25, 2019

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