Influenza Vaccine and Associated Infection and Death in California, 2024 to 2025 - Takeaways - MDSpire

Influenza Vaccine and Associated Infection and Death in California, 2024 to 2025

  • By

  • Sophie Zhu

  • Joshua Quint

  • Tomás M. León

  • Monica Sun

  • Nancy J. Li

  • Cynthia Yen

  • Brendan Flannery

  • Sascha Ellington

  • Jessie R. Chung

  • Seema Jain

  • Robert Schechter

  • Cora Hoover

  • Erin L. Murray

  • June 10, 2026

  • 0 min

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  • 1

    The 2024 to 2025 influenza season in the US saw the highest hospitalization rates since 2010 to 2011, with significant disease burden estimates.

  • 2

    Influenza vaccination is recommended annually to reduce the risk of symptomatic illness, hospitalizations, and deaths associated with influenza.

  • 3

    Public health surveillance in California linked vaccination records to laboratory-confirmed influenza cases, showing vaccination's protective effects.

  • 4

    The analysis assessed the association between influenza vaccination and both laboratory-confirmed influenza and influenza-associated deaths.

  • 5

    Influenza-associated deaths were defined as occurring within 30 days of a positive test, with specific criteria for inclusion in the analysis.

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