Morning glory syndrome with retinal detachment and literature review—a case report - Takeaways - MDSpire

Morning glory syndrome with retinal detachment and literature review—a case report

  • By

  • Yanhong Ding

  • Ai Zhang

  • June 16, 2026

  • 0 min

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  • 1

    Morning glory syndrome (MGS) is a rare congenital optic disc dysplasia characterized by optic nerve defects and distinct retinal vascular abnormalities.

  • 2

    A case report describes a 22-year-old woman with MGS presenting with retinal detachment and significantly reduced visual acuity in one eye.

  • 3

    The pathogenesis of MGS is not fully understood but may involve incomplete embryonic fissure closure and abnormal mesodermal differentiation.

  • 4

    MGS has a prevalence of 2.6 per 100,000 individuals, is more common in women, and is typically associated with poor visual acuity since childhood.

  • 5

    Diagnosis of MGS involves fundus examination and imaging techniques, revealing characteristic optic disc morphology and associated retinal changes.

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