The correlation between the atherogenic index of plasma and aortic valve calcification in the general population: a retrospective observational cohort study - Takeaways - MDSpire

The correlation between the atherogenic index of plasma and aortic valve calcification in the general population: a retrospective observational cohort study

  • By

  • Bolun Jiao

  • Rui Yu

  • Lei Li

  • Yangmin Hao

  • Guoli Du

  • Sheng Jiang

  • June 4, 2026

  • 0 min

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  • 1

    Higher plasma atherogenic index (AIP) is significantly associated with an increased risk of aortic valve calcification (AVC).

  • 2

    Each 1-unit increase in AIP correlates with a 146.0% higher risk of AVC, indicating its potential as a predictive biomarker.

  • 3

    Participants in higher AIP quartiles showed progressively increased AVC risk, with Q4 having a 2.319-fold higher risk compared to Q1.

  • 4

    Subgroup analyses confirmed that elevated AIP levels consistently relate to increased AVC risk across various demographics.

  • 5

    AIP demonstrated moderate diagnostic value for AVC risk, outperforming traditional lipid indicators like triglycerides and total cholesterol.

Original Source(s)

The correlation between the atherogenic index of plasma and aortic valve calcification in the general population: a retrospective observational cohort study

  • by Bolun Jiao, Rui Yu, Lei Li, Yangmin Hao, Guoli Du, Sheng Jiang

  • June 4, 2026

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