Risk factors for esophageal stricture after circumferential endoscopic submucosal dissection: a preliminary, multicenter, retrospective, case-control study - Takeaways - MDSpire

Risk factors for esophageal stricture after circumferential endoscopic submucosal dissection: a preliminary, multicenter, retrospective, case-control study

  • By

  • Yang Bai

  • Wei-Xing Yang

  • Min Qiao

  • Xin Yang

  • June 11, 2026

  • 0 min

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  • 1

    Post-circumferential endoscopic submucosal dissection esophageal stricture remains a significant complication despite steroid therapy.

  • 2

    A longitudinal length of circumferential involvement exceeding 50 mm is identified as an independent risk factor for post-cESD stricture.

  • 3

    The submucosal steroid pre-injection strategy shows a significant protective effect against stricture compared to combined steroid therapy.

  • 4

    Subgroup analysis indicates extensive circumferential involvement is linked to stricture in the combined steroid therapy group but not in the SSPS group.

  • 5

    Findings from this study are preliminary and require validation through larger prospective studies to confirm the results.

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