Predicting the prognosis of breast cancer patients by using nutrition-based index: a systematic review and meta-analysis

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The meta-analysis evaluated the prognostic value of the prognostic nutritional index (PNI) and controlling nutritional status (CONUT) in breast cancer.
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Higher PNI was associated with improved overall survival (OS) and disease-free survival (DFS), while higher CONUT indicated poorer OS and DFS.
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The analysis included 32 studies with 13,120 breast cancer patients, revealing substantial variability in prognostic outcomes.
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PNI and CONUT may serve as candidate prognostic indicators in breast cancer, reflecting nutritional and inflammatory status.
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The findings underscore the need for further research to clarify the predictive utility of PNI and CONUT in breast cancer management.

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