Sustained abstinence in severe ketamine use disorder following ibogaine treatment case report - Takeaways - MDSpire

Long-term Abstinence Achieved in Severe Ketamine Use Disorder After Ibogaine Intervention: A Case Study

  • By

  • Sergio R. Pérez Rosal

  • Sonya C. Faber

  • Markus Backmund

  • July 20, 2026

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  • 1

    A 30-year-old male with severe polysubstance dependence achieved long-term abstinence after ibogaine treatment.

  • 2

    The patient reported an immediate cessation of cravings for ketamine, cocaine, and alcohol following ibogaine intervention.

  • 3

    Over 17 months, assessments showed continued abstinence and significant improvements in depression and quality of life.

  • 4

    Ibogaine's therapeutic effects may arise from its unique pharmacology, including NMDA antagonism and neuroplasticity enhancement.

  • 5

    This case highlights the need for controlled clinical trials to further investigate ibogaine's safety and efficacy in treating ketamine use disorder.

Original Source(s)

Sustained abstinence in severe ketamine use disorder following ibogaine treatment case report

  • by Sergio R. Pérez Rosal, Sonya C. Faber, Markus Backmund

  • July 20, 2026

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