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1
Neurological complications in relapsing polychondritis (RP) and VEXAS syndrome are rare but can include meningitis, encephalitis, and cranial nerve palsies.
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2
Meningoencephalitis often presents severely in RP, while VEXAS syndrome may show more frequent muscle and peripheral nerve involvement.
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3
The yearly incidence of RP is estimated at 0.7 per million, with a prevalence of 4.5 per million, affecting all ages equally.
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4
Neurological symptoms in RP may appear without prior systemic symptoms, leading to retrospective diagnoses upon neurological onset.
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5
Cochlear and vestibular damage in RP can cause vertigo, tinnitus, and hearing loss, affecting up to 28% of patients over time.
