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High progesterone may be tied to syringoma

Elevated levels occurred in 29% of women with the condition compared with 6% of controls in a cross-sectional study.

  • By

  • Andrea Surnit

  • August 31, 2026

  • 3 min

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  • 1

    Women with syringoma had elevated serum progesterone levels, with 29% of patients affected compared to 6% of controls.

  • 2

    The study included 70 women, 35 with syringoma and 35 controls, aged 18 years or older with regular menstrual cycles.

  • 3

    Localized syringoma was the most common form, affecting 51% of patients, primarily in the periorbital region.

  • 4

    The study's design limited causal inference, and further research is needed to explore the role of progesterone in syringoma.

  • 5

    The researchers noted a potential hormonal association between progesterone levels and syringoma development.

Original Source(s)

High progesterone may be tied to syringoma

  • by Andrea Surnit

  • August 31, 2026

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