Direct Amoxicillin Challenges for Penicillin Allergy Through Pediatric Primary Care Group Visits: A Pilot Study - Takeaways - MDSpire
Coming Soon: Introducing MDSpire News. Learn more
Conexiant’s news site is now MDSpire News. Learn more

Pilot Study on Direct Amoxicillin Challenges for Assessing Penicillin Allergy During Pediatric Group Visits in Primary Care

  • By

  • Timothy G Chow

  • Candice Mercadel

  • Kristin S Alvarez

  • Madeline Kellam

  • David A Khan

  • Cesar Termulo

  • April 24, 2025

Share

  • 1

    A pilot study evaluated direct amoxicillin challenges for assessing penicillin allergy in pediatric group visits.

  • 2

    Ninety-five percent of participants were delabeled from penicillin allergy with no severe reactions reported.

  • 3

    Direct oral challenge testing is a safe and effective strategy for most children with penicillin allergy labels.

  • 4

    Barriers to implementing penicillin allergy testing in pediatric settings include insufficient clinic time and staffing.

  • 5

    The study highlights the need for novel strategies to improve access to penicillin allergy testing in primary care.

Original Source(s)

Direct Amoxicillin Challenges for Penicillin Allergy Through Pediatric Primary Care Group Visits: A Pilot Study

  • by Timothy G Chow, Candice Mercadel, Kristin S Alvarez, Madeline Kellam, David A Khan, Cesar Termulo

  • April 24, 2025

Related Content

Machine learning-driven risk assessment of severe Mycoplasma pneumoniae in children: analysis based on core clinical and immunological features

Endogenous Endophthalmitis and Missed Diagnoses

Retrospective study describes how endogenous endophthalmitis often presents without systemic symptoms

  • July 21, 2026

  • 3 min
Weekly HIV Therapy Meets Primary Endpoint

Patients who switched from daily antiretroviral therapy maintained virologic suppression in two phase 3 trials.