Prognostic significance of inflammation-based markers in nasopharyngeal carcinoma: a systematic review and meta-analysis - Takeaways - MDSpire

Prognostic significance of inflammation-based markers in nasopharyngeal carcinoma: a systematic review and meta-analysis

  • By

  • Yajun Wang

  • Leyu Zhang

  • Qianyu Liu

  • Yi Wu

  • July 7, 2026

  • 0 min

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  • 1

    This study systematically reviews the prognostic value of inflammation-based indices in nasopharyngeal carcinoma (NPC).

  • 2

    Nine studies involving 2,986 NPC patients were included, assessing markers like NLR, PLR, LMR, SII, SIRI, and PIV.

  • 3

    Elevated inflammation-based markers were significantly associated with poor overall survival (OS) and progression-free survival (PFS) in NPC.

  • 4

    SII and SIRI showed the strongest associations with poor outcomes, while a higher LMR was linked to better prognosis.

  • 5

    The findings suggest that integrating systemic inflammation-based biomarkers may enhance prognostic stratification in NPC.

Original Source(s)

Prognostic significance of inflammation-based markers in nasopharyngeal carcinoma: a systematic review and meta-analysis

  • by Yajun Wang, Leyu Zhang, Qianyu Liu, Yi Wu

  • July 7, 2026

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