Could HPV Be a Risk Factor for Uveitis? - Takeaways - MDSpire

Could HPV Be a Risk Factor for Uveitis?

  • July 23, 2026

  • 3 min

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  • 1

    A history of HPV infection may increase the risk of developing uveitis, according to a retrospective study published in Scientific Reports.

  • 2

    The study analyzed data from over 920,000 adults, including 460,932 with HPV infection and matched controls without HPV.

  • 3

    Patients with HPV infection were found to be 30% more likely to develop uveitis compared to matched controls over a follow-up of up to 15 years.

  • 4

    The association was strongest in men and adults aged 65 years or older, with concurrent herpes zoster infection increasing risk nearly threefold.

  • 5

    The authors caution that findings should be interpreted cautiously due to potential misclassification and inability to establish causality.

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