Impact of rehabilitation trajectory on affective and cognitive impairment after intracerebral hemorrhage: a cohort study - Takeaways - MDSpire

Impact of rehabilitation trajectory on affective and cognitive impairment after intracerebral hemorrhage: a cohort study

  • By

  • Qiuyi Jiang

  • Guangyao Shi

  • Hongli Zhang

  • Shouyue Wu

  • Chunyang Liu

  • Jian Zhang

  • Enzhou Lu

  • Chao Yuan

  • Yanchao Liang

  • Lu Wang

  • Guang Yang

  • June 10, 2026

  • 0 min

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  • 1

    This cohort study included 1,692 patients with spontaneous intracerebral hemorrhage treated between January 2018 and December 2020.

  • 2

    Patients were categorized into early rehabilitation (75.5%) and late rehabilitation (24.5%) trajectories based on modified Rankin Scale scores.

  • 3

    Late rehabilitation was associated with higher odds of cognitive impairment (OR 1.40) and depression (OR 1.96) compared to early rehabilitation.

  • 4

    Subgroup analysis indicated that males, patients with smaller hematomas, and those with higher education were more prone to impairments in the late rehabilitation group.

  • 5

    The study highlights the need for personalized rehabilitation strategies to improve neuropsychiatric outcomes in patients with late rehabilitation trajectories.

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