Adenosine Dose and Cardioversion in Pediatric Supraventricular Tachycardia: A Systematic Review and Meta-Analysis - Takeaways - MDSpire
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A Systematic Review and Meta-Analysis of Adenosine Administration and Cardioversion in Pediatric Patients with Supraventricular Tachycardia

  • By

  • Laís dos Santos

  • Thaís Martins Shehan

  • Candela Lang

  • Ricardo Sanchez Algarin

  • Ingrid Bezerra de Oliveira Ribeiro

  • Paulo Cesar Mattos Dourado de Mesquita

  • Guilherme Dagostin de Carvalho

  • June 5, 2026

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  • 1

    Supraventricular tachycardia (SVT) is the most common arrhythmia in children, with an incidence of 1 in 250 to 1 in 1000.

  • 2

    Intravenous adenosine is the first-line treatment for SVT due to its rapid onset and favorable safety profile.

  • 3

    There is significant variability in adenosine dosing across clinical settings, indicating uncertainty about optimal dosing for cardioversion.

  • 4

    The systematic review aimed to evaluate weight-based adenosine dosing and its success in achieving cardioversion in pediatric patients.

  • 5

    Subgroup analyses were conducted to assess cardioversion outcomes based on different weight-based adenosine dose categories.

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