Independent validation of CT radiomics models in colorectal liver metastases: predicting local tumour progression after ablation - Takeaways - MDSpire

Independent validation of CT radiomics models in colorectal liver metastases: predicting local tumour progression after ablation

  • By

  • Denise J. van der Reijd

  • Corentin Guerendel

  • Femke C. R. Staal

  • Milou P. Busard

  • Mateus De Oliveira Taveira

  • Elisabeth G. Klompenhouwer

  • Koert F. D. Kuhlmann

  • Adriaan Moelker

  • Cornelis Verhoef

  • Martijn P. A. Starmans

  • Doenja M. J. Lambregts

  • Regina G. H. Beets-Tan

  • Sean Benson

  • Monique Maas

  • November 21, 2023

  • 0 min

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  • 1

    Colorectal liver metastases (CRLM) are primarily treated with resection, but thermal ablation is a viable alternative for ineligible patients.

  • 2

    Local tumor progression (LTP) rates after thermal ablation of CRLM range from 6% to 46%, complicating timely detection and treatment.

  • 3

    The study aimed to validate clinical-radiomics prediction models for LTP after thermal ablation using independent internal and external cohorts.

  • 4

    The combined clinical-radiomics model demonstrated the highest performance with a concordance statistic of 0.78 in predicting LTP.

  • 5

    A multicenter retrospective study was conducted, adhering to strict inclusion and exclusion criteria to ensure comparable patient cohorts.

Original Source(s)

Independent validation of CT radiomics models in colorectal liver metastases: predicting local tumour progression after ablation

  • by Denise J. van der Reijd, Corentin Guerendel, Femke C. R. Staal, Milou P. Busard, Mateus De Oliveira Taveira, Elisabeth G. Klompenhouwer, Koert F. D. Kuhlmann, Adriaan Moelker, Cornelis Verhoef, Martijn P. A. Starmans, Doenja M. J. Lambregts, Regina G. H. Beets-Tan, Sean Benson, Monique Maas

  • November 21, 2023

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