Disseminated Mycobacterium kansasii infection with osseous involvement in anti-interferon-γ autoantibody-associated adult-onset immunodeficiency: a case report and literature review - Takeaways - MDSpire

Disseminated Mycobacterium kansasii infection with osseous involvement in anti-interferon-γ autoantibody-associated adult-onset immunodeficiency: a case report and literature review

  • By

  • Jian Wang

  • Keying Lin

  • Yidan Zhong

  • Zhiyu Wu

  • Tao Lu

  • WeiLi Lu

  • Weiguo Wang

  • Cuifang Ma

  • June 23, 2026

  • 0 min

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  • 1

    Anti–interferon-γ autoantibody-associated adult-onset immunodeficiency predisposes patients to recurrent opportunistic infections.

  • 2

    Disseminated Mycobacterium kansasii infection can mimic malignancy, leading to diagnostic delays.

  • 3

    A 53-year-old man with chronic hepatitis B presented with symptoms and imaging suggestive of lung cancer.

  • 4

    Repeated pathological examinations failed to confirm malignancy, leading to a diagnosis of disseminated M. kansasii.

  • 5

    Early pathogen detection and anti–IFN-γ autoantibody testing may reduce diagnostic delays in similar cases.

Original Source(s)

Disseminated Mycobacterium kansasii infection with osseous involvement in anti-interferon-γ autoantibody-associated adult-onset immunodeficiency: a case report and literature review

  • by Jian Wang, Keying Lin, Yidan Zhong, Zhiyu Wu, Tao Lu, WeiLi Lu, Weiguo Wang, Cuifang Ma

  • June 23, 2026

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