Couple-level dyslipidemia and embryological and cumulative pregnancy outcomes in IVF/ICSI cycles: a single-center retrospective cohort study - Takeaways - MDSpire

Couple-level dyslipidemia and embryological and cumulative pregnancy outcomes in IVF/ICSI cycles: a single-center retrospective cohort study

  • By

  • Ruobing Lei

  • Shuyi Chen

  • Weihong Li

  • June 18, 2026

  • 0 min

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  • 1

    The study analyzed 209 infertile couples undergoing their first IVF/ICSI cycle to assess the impact of couple-level dyslipidemia on pregnancy outcomes.

  • 2

    Female dyslipidemia was linked to longer stimulation duration, higher gonadotropin doses, and lower fertilization rates in IVF/ICSI cycles.

  • 3

    Male dyslipidemia correlated with fewer transferable embryos and lower fertilization rates, affecting overall embryological outcomes.

  • 4

    Couples with bilateral dyslipidemia showed significantly higher odds of cumulative miscarriage and lower odds of cumulative live birth.

  • 5

    The findings suggest that dyslipidemia in either partner negatively impacts embryological and cumulative pregnancy outcomes in IVF/ICSI.

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