Utilization of Mesenchymal Stem Cells and Their Exosomes in Treating Pediatric ARDS: A Review of Translational Research and Evolving Nursing Responsibilities

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Pediatric ARDS is a severe lung condition with high mortality and limited conventional treatments.
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Mesenchymal stem cells (MSCs) and their exosomes (MSC-Exos) show promise for treating pediatric ARDS due to their anti-inflammatory and tissue-repair functions.
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The therapeutic effects of MSCs in pediatric ARDS primarily involve immunomodulation and paracrine signaling rather than direct cellular engraftment.
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MSC-Exos have advantages over whole MSCs, including lower immunogenicity and enhanced stability, making them a favorable therapeutic option.
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Nursing roles are evolving to include advanced management of biotherapeutic modalities, requiring new competencies in cellular biology and patient care.

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