New Medications for Dry Eye and Presbyopia - Takeaways - MDSpire
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New Medications for Dry Eye and Presbyopia
Topical miotics are approved for use in all adults with presbyopia, including post-LASIK patients and pseudophakes, and acoltremon is a treatment option for multiple dry eye subtypes, either as primary therapy or adjunctive treatment.
By
Sarah Fackler, managing editor, Optometric Management
New topical prescription therapies for presbyopia and dry eye disease include pilocarpine, aceclidine, and acoltremon.
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Pilocarpine 0.4% shows significant improvement in near visual acuity, with 52.9% of patients achieving 20/40 DCNVA or better by day 15.
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Aceclidine 1.44% has a dosing regimen of 2 drops once daily and demonstrates a rapid onset of effect, with 71% of participants improving within 0.5 hours.
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Acoltremon 0.003% stimulates tear production and met primary endpoints in phase 3 trials, showing significant improvements in dry eye symptoms.
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Topical miotics are approved for all adults with presbyopia, including post-LASIK patients, while acoltremon is suitable for various dry eye subtypes.
