Comorbidities Worsen Carpal Tunnel Outcomes

Patients with systemic diseases had worse symptoms and function before and following surgery, though improvement after release was similar.

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Patients with systemic diseases had worse symptoms and functional limitations before and after carpal tunnel release compared to those without.
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Both groups experienced similar degrees of improvement post-surgery, despite the higher severity in patients with systemic diseases.
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The study included 48 patients, evenly divided between those with and without systemic diseases, matched for age and sex.
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Systemic conditions may worsen nerve compression through mechanisms like inflammation, neuropathy, and tissue swelling.
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The study's limitations include a small sample size and potential selection bias, affecting the generalizability of the findings.

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