Influenza vaccine effectiveness against hospitalization in children aged 6–72 months: a test-negative study in the Southern Italy, 2022–2026 - Takeaways - MDSpire
Coming Soon: Introducing MDSpire News. Learn more
Conexiant’s news site is now MDSpire News. Learn more

Effectiveness of influenza vaccination in preventing hospitalization among children aged 6–72 months: a test-negative study in Southern Italy, 2022–2026

  • By

  • Francesca Fortunato

  • Angelo Campanozzi

  • Angelo Acquafredda

  • Matteo Mariano

  • Valeria delli Carri

  • Tiziana Rollo

  • Loris Micelli

  • Dalila Tedeschi

  • Rosa Prato

  • Domenico Martinelli

  • October 9, 2026

Share

  • 1

    The study assessed influenza vaccine effectiveness against hospitalization among children aged 6–72 months across four seasons in Foggia, southern Italy.

  • 2

    Among 935 hospitalized children tested for influenza, 207 were influenza-positive cases and 728 were influenza-negative controls.

  • 3

    Pooled adjusted vaccine effectiveness against influenza-associated hospitalization was 62.5% for at least 1 vaccine dose and 61.9% for full vaccination.

  • 4

    Adjusted effectiveness was higher for LAIV than IIV: 80.3% versus 50.9% after at least 1 dose.

  • 5

    Subtype-specific effectiveness was 82.3% against A(H1N1)pdm09 and 43.5% against A(H3N2); the latter estimate was not statistically significant.

Original Source(s)

Influenza vaccine effectiveness against hospitalization in children aged 6–72 months: a test-negative study in the Southern Italy, 2022–2026

  • by Francesca Fortunato, Angelo Campanozzi, Angelo Acquafredda, Matteo Mariano, Valeria delli Carri, Tiziana Rollo, Loris Micelli, Dalila Tedeschi, Rosa Prato, Domenico Martinelli

  • October 9, 2026

Related Content

CDC recommends 2026–2027 COVID vaccines for all adults

Updated guidance recommends vaccination for adults aged 18 years and older, with pediatric recommendations based on immune status.

Pennsylvania Restricts Vaping Products as States Strengthen Youth Protections

Parental fear of progression in juvenile idiopathic arthritis and type 1 diabetes