Effect of RAS inhibitors on retinal microvasculature in DKD using AI-based ultra-wide-field images - Takeaways - MDSpire

Effect of RAS inhibitors on retinal microvasculature in DKD using AI-based ultra-wide-field images

  • By

  • Yan Liu

  • Xinyu Zhao

  • Haiyun Wang

  • Jie Ma

  • Peng Xia

  • Xingwang Gu

  • Youxin Chen

  • Limeng Chen

  • June 26, 2026

  • 0 min

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  • 1

    This pilot study assessed the impact of RAS inhibitors on retinal microvascular parameters in diabetic kidney disease patients using AI-enhanced imaging.

  • 2

    Twenty-seven patients with diabetic kidney disease were enrolled, with a mean age of 55.7 years and a mean diabetes duration of 9.9 years.

  • 3

    Significant decreases in venous fractal dimension and tortuosity were observed after 12 weeks of RAS inhibitor treatment in specific patient groups.

  • 4

    The study utilized ultra-wide-field fundus imaging and AI analysis to quantify retinal microvascular changes and their correlation with renal indicators.

  • 5

    Findings suggest potential vascular-specific responses to RAS inhibitors, highlighting the need for further exploration of retinal imaging biomarkers.

Original Source(s)

Effect of RAS inhibitors on retinal microvasculature in DKD using AI-based ultra-wide-field images

  • by Yan Liu, Xinyu Zhao, Haiyun Wang, Jie Ma, Peng Xia, Xingwang Gu, Youxin Chen, Limeng Chen

  • June 26, 2026

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