Machine and deep learning based on magnetic resonance imaging to segment glioblastoma and predict the spread of recurrence: a multicenter retrospective protocol - Takeaways - MDSpire

Machine and deep learning based on magnetic resonance imaging to segment glioblastoma and predict the spread of recurrence: a multicenter retrospective protocol

  • By

  • Luana Conte

  • Erica Lo Turco

  • Rosaria V. Abbritti

  • Caterina Accettura

  • Giuseppe Raso

  • Edvige Iaboni

  • Ugo De Giorgi

  • Giorgio De Nunzio

  • Donato Cascio

  • Maria Caffo

  • July 10, 2026

  • 0 min

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  • 1

    The study focuses on glioblastoma (GB), an aggressive brain tumor with high recurrence rates and limited survival.

  • 2

    Machine Learning (ML) and Deep Learning (DL) techniques will be applied to MRI data to predict recurrence spread in GB patients.

  • 3

    A multicenter retrospective collection of clinical and radiological variables will be performed for eligible GB patients.

  • 4

    The study aims to develop a semi-automatic segmentation tool for tumor delineation in MRI to standardize volume measurement.

  • 5

    Model performance will be assessed using various metrics, including Area Under the Curve (AUC) and Dice score for segmentation.

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