Triglyceride–glucose related index and its association with coronary heart disease risk in patients with metabolic dysfunction-associated steatotic liver disease: a retrospective analysis based on type 2 diabetes mellitus - Takeaways - MDSpire

Triglyceride–glucose related index and its association with coronary heart disease risk in patients with metabolic dysfunction-associated steatotic liver disease: a retrospective analysis based on type 2 diabetes mellitus

  • By

  • Xuying Zhao

  • Yang Hong

  • Saiyan Bian

  • Hui Jiao

  • Xingjian Zhong

  • Wenkai Ni

  • June 16, 2026

  • 0 min

Share

  • 1

    The triglyceride–glucose (TyG) index is a significant marker of insulin resistance associated with coronary heart disease (CHD) risk in patients with metabolic dysfunction-associated steatotic liver d

  • 2

    In a study of 812 patients with MASLD, TyG was positively correlated with CHD risk, showing an odds ratio (OR) of 2.035.

  • 3

    Type 2 diabetes mellitus (T2DM) was also linked to increased CHD risk, with an OR of 2.107, indicating a strong association.

  • 4

    The association between TyG and CHD risk was significantly stronger in patients with T2DM, with an OR of 3.34 compared to 1.89 in those without T2DM.

  • 5

    Receiver operating characteristic (ROC) analysis identified TyG cut-off values of 7.992 for patients without T2DM and 9.005 for those with T2DM, indicating increased CHD risk.

Original Source(s)

Triglyceride–glucose related index and its association with coronary heart disease risk in patients with metabolic dysfunction-associated steatotic liver disease: a retrospective analysis based on type 2 diabetes mellitus

  • by Xuying Zhao, Yang Hong, Saiyan Bian, Hui Jiao, Xingjian Zhong, Wenkai Ni

  • June 16, 2026

Related Content

AI Screening for Diabetic Retinopathy

Chronotropic incompetency during stress echocardiography: a new paradigm for mortality and cardiac event prediction?

Tracking Retinal Health With Wearable Technology

The use of wearable devices for health monitoring has attracted significant interest from patients, physicians, and other healthcare professionals because of their potential to usher in a new era of personalized, accessible, and convenient care. This article explores the use of wearable technology for monitoring retinal health, both through direct assessment of ocular parameters—such as visual field testing and imaging—and through systemic monitoring of surrogate markers of retinal health.