Evaluating the Utility of the C-Reactive Protein to Albumin Ratio in Retinal Vein Occlusion Assessment - Takeaways - MDSpire

Evaluating the Utility of the C-Reactive Protein to Albumin Ratio in Retinal Vein Occlusion Assessment

  • By

  • Esra Vural

  • Leyla Hazar

  • November 25, 2025

  • 0 min

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  • 1

    Retinal vein occlusion (RVO) is a prevalent microvascular disease, with varying rates among ethnic groups and increasing incidence with age.

  • 2

    C-reactive protein (CRP) and albumin serve as acute phase reactants, indicating systemic inflammation and are linked to cardiovascular diseases.

  • 3

    The study aimed to evaluate the CRP/albumin ratio and systemic immune-inflammation index (SII) as inflammation markers in RVO patients.

  • 4

    Results showed that the CRP/albumin ratio was significantly higher in RVO patients compared to healthy controls, indicating its potential as a prognostic marker.

  • 5

    The optimal cut-off value of the CRP/albumin ratio for RVO estimation was determined to be 0.42, with 79% sensitivity and 55% specificity.

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