Comparison of early clinical and optical quality-related outcomes after SMILE using VisuMax 800 versus VisuMax 500 for myopia and low-to-moderate astigmatism in a Chinese population: a single-center retrospective study - Takeaways - MDSpire
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Evaluation of Initial Clinical Outcomes and Optical Quality Metrics Following SMILE with VisuMax 800 Compared to VisuMax 500 for Myopia and Low-to-Moderate Astigmatism in a Chinese Cohort: A Retrospective Single-Center Analysis

  • By

  • Xuanyu Yang

  • Jiabin Leng

  • Yuchen Mei

  • Fei Peng

  • Yifan Xie

  • Linlin Liu

  • Linhua Wan

  • Liping Liu

  • Wentian Zhou

  • Hui Zhang

  • April 30, 2026

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  • 1

    The study compared early clinical outcomes of SMILE using VisuMax 800 and VisuMax 500 in 200 Chinese patients with myopia and low-to-moderate astigmatism.

  • 2

    Both laser platforms demonstrated similar postoperative uncorrected and corrected distance visual acuity, safety index, and efficacy index at 3 months postoperatively.

  • 3

    The SMILE Pro group (VisuMax 800) had significantly shorter lenticule creation time and lower optical zone decentration compared to the SMILE group (VisuMax 500).

  • 4

    Postoperative vertical coma and residual cylindrical error were lower in the SMILE Pro group, indicating improved optical quality outcomes.

  • 5

    The findings suggest that while both platforms are effective, the VisuMax 800 may offer advantages in certain optical quality metrics and should be further studied.

Original Source(s)

Comparison of early clinical and optical quality-related outcomes after SMILE using VisuMax 800 versus VisuMax 500 for myopia and low-to-moderate astigmatism in a Chinese population: a single-center retrospective study

  • by Xuanyu Yang, Jiabin Leng, Yuchen Mei, Fei Peng, Yifan Xie, Linlin Liu, Linhua Wan, Liping Liu, Wentian Zhou, Hui Zhang

  • April 30, 2026

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