Sex-specific echocardiographic remodeling and prognostic value of left ventricular sphericity, pressure–dimension index, and myocardial work after durable LVAD implantation - Takeaways - MDSpire

Sex-specific echocardiographic remodeling and prognostic value of left ventricular sphericity, pressure–dimension index, and myocardial work after durable LVAD implantation

  • By

  • Mahmoud Jaber

  • Ahmed F. A. Mohammed

  • Yusuf Shieba

  • Ajay Moza

  • Alish Kolashov

  • Rashad Zayat

  • June 23, 2026

  • 0 min

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  • 1

    The study analyzed 103 adults undergoing durable LVAD implantation, focusing on sex-specific remodeling patterns and prognostic value of ventricular geometry.

  • 2

    Men showed adverse changes in left ventricular sphericity index and a significant decline in pressure-dimension index post-implantation.

  • 3

    Women maintained stable left ventricular sphericity and higher absolute pressure-dimension index at 6 months after LVAD implantation.

  • 4

    Preoperative left ventricular sphericity index was independently associated with mortality, while global work index predicted both mortality and postoperative right heart failure.

  • 5

    Findings suggest that LV geometry and myocardial work may aid in future risk stratification, although results require cautious interpretation due to small sample size.

Original Source(s)

Sex-specific echocardiographic remodeling and prognostic value of left ventricular sphericity, pressure–dimension index, and myocardial work after durable LVAD implantation

  • by Mahmoud Jaber, Ahmed F. A. Mohammed, Yusuf Shieba, Ajay Moza, Alish Kolashov, Rashad Zayat

  • June 23, 2026

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