Altered Microbiome Signature in Cushing's Syndrome Persists Beyond Remission - Takeaways - MDSpire

Altered Microbiome Signature in Cushing's Syndrome Persists Beyond Remission

  • By

  • German Rubinstein

  • Ilias Lagkouvardos

  • Evangelia Intze

  • Andrea Osswald

  • Stephanie Zopp

  • Leah Theresa Braun

  • Adriana Albani

  • Heike Künzel

  • Anna Riester

  • Felix Beuschlein

  • Martin Reincke

  • Katrin Ritzel

  • December 23, 2024

  • 0 min

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  • 1

    Cushing's syndrome (CS) is linked to metabolic and cardiovascular issues due to chronic hypercortisolism.

  • 2

    The study analyzed gut microbiome changes in 18 CS patients before and after surgical remission compared to obese and healthy controls.

  • 3

    Patients with active CS exhibited a disturbed gut microbiome profile, which persisted even after achieving biochemical remission.

  • 4

    Microbial dysbiosis in CS patients may contribute to ongoing health risks despite successful treatment.

  • 5

    The findings suggest potential for probiotic interventions to help restore a healthy gut microbiome in CS patients post-remission.

Original Source(s)

Altered Microbiome Signature in Cushing's Syndrome Persists Beyond Remission

  • by German Rubinstein, Ilias Lagkouvardos, Evangelia Intze, Andrea Osswald, Stephanie Zopp, Leah Theresa Braun, Adriana Albani, Heike Künzel, Anna Riester, Felix Beuschlein, Martin Reincke, Katrin Ritzel

  • December 23, 2024

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