Mycobacterium abscessus infection in a young man with cystic fibrosis: a case report and literature review - Takeaways - MDSpire

Mycobacterium abscessus infection in a young man with cystic fibrosis: a case report and literature review

  • By

  • Ling Luo

  • Zhuoyao Guo

  • Weicheng Chen

  • Yanghong Zheng

  • Chen Chen

  • Qiang Li

  • Na Wang

  • Yingqun Ji

  • Jing Hua

  • May 26, 2026

  • 0 min

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  • 1

    Cystic fibrosis (CF) is a rare genetic disorder caused by CFTR gene mutations, leading to respiratory and digestive complications.

  • 2

    A 21-year-old man in China was diagnosed with CF after presenting with recurrent cough, fever, and bronchiectasis.

  • 3

    Metagenomic sequencing identified Mycobacterium abscessus and Staphylococcus aureus in the patient's bronchoalveolar lavage fluid.

  • 4

    The patient achieved clinical stability with a quadruple antimycobacterial regimen, despite deferring CFTR modulator therapy due to financial constraints.

  • 5

    This case highlights the importance of early CF diagnosis and personalized treatment strategies, especially in non-Caucasian populations.

Original Source(s)

Mycobacterium abscessus infection in a young man with cystic fibrosis: a case report and literature review

  • by Ling Luo, Zhuoyao Guo, Weicheng Chen, Yanghong Zheng, Chen Chen, Qiang Li, Na Wang, Yingqun Ji, Jing Hua

  • May 26, 2026

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