Interaction between parental preconception and prenatal smoking and alcohol use on autism-like behaviour in preschoolers: a cross-sectional study in Huizhou, China - Takeaways - MDSpire

Interaction between parental preconception and prenatal smoking and alcohol use on autism-like behaviour in preschoolers: a cross-sectional study in Huizhou, China

  • By

  • Shuang Wu

  • Huiting Chen

  • Jinming Liu

  • Ruoqing Chen

  • Weiying Liu

  • Yulan Wu

  • Zizi Liu

  • Feixiang Zeng

  • Dongyan Wen

  • Jiarong Lin

  • Lvping Li

  • Yu Jin

  • May 26, 2026

  • 0 min

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  • 1

    This study analyzed 19,089 preschool children to assess the impact of parental smoking and alcohol consumption on autism-like behaviors.

  • 2

    Maternal prenatal passive smoking and paternal smoking history were linked to significantly higher odds of autism-like behavior in children.

  • 3

    A negative additive interaction was found between maternal smoking cessation during pregnancy and concurrent alcohol consumption.

  • 4

    The findings highlight the importance of reducing parental tobacco and alcohol exposure to prevent autism spectrum disorder.

  • 5

    The study suggests including paternal smoking history and maternal passive smoking in autism risk assessments and prenatal health guidance.

Original Source(s)

Interaction between parental preconception and prenatal smoking and alcohol use on autism-like behaviour in preschoolers: a cross-sectional study in Huizhou, China

  • by Shuang Wu, Huiting Chen, Jinming Liu, Ruoqing Chen, Weiying Liu, Yulan Wu, Zizi Liu, Feixiang Zeng, Dongyan Wen, Jiarong Lin, Lvping Li, Yu Jin

  • May 26, 2026

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