Differences in clinical characteristics and cardiovascular disease risk prediction among Chinese women with polycystic ovary syndrome phenotypes: a cross-sectional study - Takeaways - MDSpire

Differences in clinical characteristics and cardiovascular disease risk prediction among Chinese women with polycystic ovary syndrome phenotypes: a cross-sectional study

  • By

  • Ziye Gong

  • Danyang Li

  • Xuan Li

  • Jinjin Tian

  • Jing Guo

  • Yuying Zhao

  • Yin Lu

  • Shan Gao

  • Ming Li

  • April 10, 2026

  • 0 min

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  • 1

    The study analyzed 206 Chinese women with PCOS, classifying them into four phenotypes based on the Rotterdam criteria.

  • 2

    Phenotypes A, B, and C exhibited significantly higher BMI, blood pressure, and CVD risk compared to phenotype D.

  • 3

    Lifetime CVD risk scores were notably higher in phenotypes A, B, and C, with values of 15.55%, 17.65%, and 17.30%, respectively.

  • 4

    BMI, HOMA-IR, and uric acid levels significantly mediated the relationship between PCOS phenotypes and CVD risk.

  • 5

    Regular CVD risk assessments are recommended for women with different PCOS phenotypes to guide individualized treatment strategies.

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