Accumulation of embryos to improve outcomes in advanced-age women undergoing IVF/ICSI cycles: a retrospective cohort study - Takeaways - MDSpire

Accumulation of embryos to improve outcomes in advanced-age women undergoing IVF/ICSI cycles: a retrospective cohort study

  • By

  • Mingya Cao

  • Yue Wang

  • Liang Zhou

  • Kexin Xing

  • Huanjun Li

  • Yuanyuan Liu

  • Qingyun Sun

  • Xuli Zhu

  • Zhiming Zhao

  • July 7, 2026

  • 0 min

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  • 1

    The study analyzed 970 advanced-age women undergoing IVF/ICSI to assess the impact of embryo accumulation on reproductive outcomes.

  • 2

    Participants were divided into an embryo accumulation group and a control group, with 299 matched pairs analyzed after propensity score matching.

  • 3

    Results indicated that the embryo accumulation group had significantly higher cumulative live birth rates and cumulative clinical pregnancy rates.

  • 4

    The study found no significant difference in miscarriage rates between the two groups, suggesting similar safety profiles.

  • 5

    The benefits of embryo accumulation were most pronounced when the number of accumulated embryos did not exceed two.

Original Source(s)

Accumulation of embryos to improve outcomes in advanced-age women undergoing IVF/ICSI cycles: a retrospective cohort study

  • by Mingya Cao, Yue Wang, Liang Zhou, Kexin Xing, Huanjun Li, Yuanyuan Liu, Qingyun Sun, Xuli Zhu, Zhiming Zhao

  • July 7, 2026

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