Rethinking Sudden Death in Heart Failure With Mildly Reduced or Preserved Ejection Fraction - Takeaways - MDSpire

Rethinking Sudden Death in Heart Failure With Mildly Reduced or Preserved Ejection Fraction

  • By

  • Gregg C. Fonarow

  • June 1, 2026

  • 0 min

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  • 1

    Sudden death in heart failure patients with mildly reduced or preserved ejection fraction is poorly understood and traditionally viewed as unpredictable.

  • 2

    A post hoc analysis of the FINEARTS-HF trial examined clinical changes preceding sudden death compared to survivors and other death causes.

  • 3

    Patients who experienced sudden death showed measurable declines in functional status and rising natriuretic peptide levels before death.

  • 4

    Similar clinical deteriorations were observed in patients who died from heart failure-related or other cardiovascular causes.

  • 5

    The findings highlight the need for improved risk prediction methods that integrate clinical data with biomarkers and advanced technologies.

Original Source(s)

Rethinking Sudden Death in Heart Failure With Mildly Reduced or Preserved Ejection Fraction

  • by Gregg C. Fonarow

  • June 1, 2026

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