Clinical improvement of photophobia with galcanezumab in episodic and chronic migraine - Takeaways - MDSpire

Clinical improvement of photophobia with galcanezumab in episodic and chronic migraine

  • By

  • Elif Ilgaz Aydınlar

  • Pınar Yalınay Dikmen

  • Aysenur Sahin

  • Kerem Birısık

  • June 1, 2026

  • 0 min

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  • 1

    The study evaluated photophobia changes in patients with episodic and chronic migraine treated with galcanezumab.

  • 2

    A total of 77 patients participated, with 47 completing the study and showing significant reductions in monthly headache days.

  • 3

    UPSIS-12 scores declined significantly, indicating improvement in photophobia symptoms among responders to galcanezumab.

  • 4

    Responders exhibited notable reductions in ictal photophobia, while interictal sensory symptoms remained largely unchanged.

  • 5

    Galcanezumab treatment was well tolerated, with no serious adverse events reported during the study period.

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