Discrepancies in Cardiac Output Measurements: A Comparison of Pressure Recording Analytical Method and Pulmonary Artery Thermodilution in Low Cardiac Output Patients - Initial Findings from a Prospective Observational Pilot Study - Takeaways - MDSpire

Discrepancies in Cardiac Output Measurements: A Comparison of Pressure Recording Analytical Method and Pulmonary Artery Thermodilution in Low Cardiac Output Patients - Initial Findings from a Prospective Observational Pilot Study

  • By

  • Maximilian J. G. Oremek

  • Jacqueline Kruse

  • Miriam Silaschi

  • Claudia Neumann

  • Sven Klaschik

  • Marcus Thudium

  • January 22, 2026

  • 0 min

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  • 1

    The study evaluated the feasibility of the pressure recording analytical method (PRAM) for cardiac output measurement in patients with severely impaired left ventricular function.

  • 2

    Data acquisition using PRAM was highly feasible, achieving a 98.8% success rate in collecting concurrent measurements with pulmonary artery catheter (PAC) data.

  • 3

    PRAM significantly underestimated cardiac output by an average of -2.02 L/min compared to PAC, with a high percentage error of 134.3%.

  • 4

    The trending ability of PRAM was poor, with only 36.6% four-quadrant concordance and 10.1% polar concordance with PAC measurements.

  • 5

    Findings suggest that PRAM's accuracy may be compromised in patients with low ejection fraction, warranting further investigation in this population.

Original Source(s)

Discrepancies in Cardiac Output Measurements: A Comparison of Pressure Recording Analytical Method and Pulmonary Artery Thermodilution in Low Cardiac Output Patients - Initial Findings from a Prospective Observational Pilot Study

  • by Maximilian J. G. Oremek, Jacqueline Kruse, Miriam Silaschi, Claudia Neumann, Sven Klaschik, Marcus Thudium

  • January 22, 2026

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